Molecules to Missiles

09/20/2017

CDI funding tests the promise of nanomedicine in brain tumor treatment....More

Immune System: The Body's New Super Hero?

05/30/2017

The journal Science Translational Medicine recently published a study showing promise for immunotherapy in treating recurrent acute myeloid leukemia (AML) in adults. The study’s lead author Rizwan Romee, MD, and senior author Todd Fehniger, MD, PhD, from the division of oncology of Washington University School of Medicine, barely let the ink dry before they were on to their next challenge. In collaboration with Jeffrey Bednarski, MD, PhD, pediatrics, they submitted a proposal to and received funding from the Children’s Discovery Institute to pursue the same study in children....More

Riding for Vivian

07/14/2016

Vivian Keith is a feisty, sometimes stubborn 3-year-old with curly-cue hair and a twin brother named Lane. Her mom, Ginger, always knew Vivian was a determined little girl but she didn’t realize the depth of that determination until Vivian had to battle cancer....More

CDI Researchers Now Part of Pediatric Neuro-Oncology Consortium

03/24/2016

When the Washington University School of Medicine joined the Pacific Pediatric Neuro-Oncology Consortium, it brought with it three CDI-funded physician-scientists who now have access to the most cutting-edge brain tumor therapies for the children of St. Louis and surrounding region. ...More

New Research on Pediatric Brain Tumors Underway

09/15/2015

According to Dr. Rubin, MD, PhD, pediatrics, despite decades of research, we still have little understanding of the fundamental mechanisms that drive the genesis of pediatric brain tumors and the requirements for effective treatment. Now, the discovery of a key player in making brain tumors resistant to treatment by Washington University School of Medicine’s Albert Kim, MD, PhD, neurosurgery, will inform a CDI study that brings Dr. Kim together with Dr. Rubin, developmental biologist Kristen Kroll, PhD, and Hiroko Yano, PhD, an expert in neuro-epigenetics, as co-principal investigators to crack the code of what happens during brain stem cell differentiation that sets a child on the path to developing this malignant brain tumor. ...More

Inspired by a Superhero

02/24/2015

Learn about how one little brave little boy's cancer fight inspires our pediatric cancer research seeking answers for a devastating diagnosis....More

Pedal the Cause for Pediatric Cancer Research

06/24/2014

Private support for pediatric cancer research has never been more critical. And, you can make a difference....More

A Tale of Two Leukemias

05/21/2014

Two stories of struggle and survival, two CDI researchers looking for answers....More

Infants With Leukemia Inherit Susceptibility

02/19/2014

CDI-funded research, presented at the 2013 CDI Investor Symposium and recently published in the online journal Leukemia, indicates that babies with leukemia have inherited a genetic predisposition that makes them highly susceptible to the disease. ...More

CDI Hosts First Visiting Investigator

02/14/2014

In the spirit of its collaborative vision, the Children’s Discovery Institute sponsored its first visiting researcher in January: David Ingram, MD, the Hugh McK Landon Professor of Pediatrics and of Biochemistry and Molecular Biology, director of the Section of Neonatal-Perinatal Medicine at Indiana University School of Medicine....More

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