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Research Highlights
The Epicenter of Cellular Imaging

With the October 2015 opening of the Washington University Center for Cellular Imaging (WUCCI), researchers throughout the Washington University School of Medicine campus, including those funded by the Children’s Discovery Institute (CDI), have access to a shared technology resource center where the sole focus is the advancement of imaging technologies in support of their pediatric research studies. Since receiving CDI funding last fall, WUCCI has helped 18 CDI center members and six currently funded CDI investigators take advantage of its new and illuminating resource....Learn More

Seeking a Fighting Chance for Cystic Fibrosis Patients

When you have two great passions — children and science — going to medical school and becoming a pediatrician seem like obvious choices. But, choosing a pediatric specialty proved more challenging for Jessica Pittman, MD, MPH, pediatrics, until she met Dylan. ...Learn More

New Research on Pediatric Brain Tumors Underway

According to Dr. Rubin, MD, PhD, pediatrics, despite decades of research, we still have little understanding of the fundamental mechanisms that drive the genesis of pediatric brain tumors and the requirements for effective treatment. Now, the discovery of a key player in making brain tumors resistant to treatment by Washington University School of Medicine’s Albert Kim, MD, PhD, neurosurgery, will inform a CDI study that brings Dr. Kim together with Dr. Rubin, developmental biologist Kristen Kroll, PhD, and Hiroko Yano, PhD, an expert in neuro-epigenetics, as co-principal investigators to crack the code of what happens during brain stem cell differentiation that sets a child on the path to developing this malignant brain tumor. ...Learn More

Moving Toward Personalized Medicine

Learn how a little boy helped researchers gain a greater understanding of our immune system....Learn More

Healing a Broken Heart

Can we put immune cells to work to reverse pediatric cardiomyopathy? One CDI researcher intends to find out....Learn More

News & Events
New CDI Studies Underway The Children’s Discovery Institute recently allocated $2.8 million toward comprehensive genome analysis to improve the ability to diagnosis birth defects, toward work that will seek to identify biomarkers of cognitive dysfunction in survivors of pediatric brain tumors and more.... CDI More Info
CDI Researcher Receives Prestigious Award to Further Malaria Research Audrey R. Odom, MD, PhD, a noted CDI-funded malaria researcher at Washington University School of Medicine in St. Louis, has received a five-year, $500,000 award from the Burroughs Wellcome Fund to further her research into the parasitic disease. ... CDI More Info
Riding for Vivian Vivian Keith is a feisty, sometimes stubborn 3-year-old with curly-cue hair and a twin brother named Lane. Her mom, Ginger, always knew Vivian was a determined little girl but she didn’t realize the depth of that determination until Vivian had to battle cancer.... CDI More Info
Development of Gut Microbes and Gut Immunity Linked CDI-funded research studying twins from birth to age 2 has shown that the gut’s immune system develops in sync with the gut’s tens of trillions of microbes.... CDI More Info
Antibiotic Resistance Hot Spots Identified CDI investigator Gautam Dantas, PhD, led a study that surveyed ecosystems of bacteria and their capacity to resist antibiotics in low resource communities and identified areas ripe for bacteria to shuffle and share their resistance genes.... CDI More Info