Antibiotics Warranted for Kids with Minor Staph Infections

09/26/2017

A former CDI faculty scholar and her research team have found that prescribing antibiotics is warranted for children with minor staph infections. The drugs help to reduce the risk of recurrent infections....More

Two Experts. One Protein. And the Mission That Binds Them

09/20/2017

A CDI resaerch team has embarked on a drug discovery journey that may lead to new treatment for pediatric nonalcoholic fatty liver disease (NFLD. This serious condition is a troubling consequence of the rise in childhood obesity that can lead to diminished liver function later in life. According to the Centers for Disease Control and Prevention, one in five school-aged children (ages 6-19) is obese. ...More

CDI Leaders Identify Surprising Culprit in Nerve Cell Damage

03/31/2017

In new research, scientists at Washington University School of Medicine who play important leadership roles in the Children's Discovery Institute uncovered findings that suggest ways to block nerve cell damage in neurodegenerative diseases....More

Audrey Odom John: At the Global Forefront of Ending Malaria

02/01/2017

See where a 2009 Faculty Scholar Award helped take this CDI researcher. ...More

CDI Researcher Receives Prestigious Award to Further Malaria Research

07/26/2016

Audrey R. Odom, MD, PhD, a noted CDI-funded malaria researcher at Washington University School of Medicine in St. Louis, has received a five-year, $500,000 award from the Burroughs Wellcome Fund to further her research into the parasitic disease. ...More

Development of Gut Microbes and Gut Immunity Linked

06/01/2016

CDI-funded research studying twins from birth to age 2 has shown that the gut’s immune system develops in sync with the gut’s tens of trillions of microbes....More

Antibiotic Resistance Hot Spots Identified

05/13/2016

CDI investigator Gautam Dantas, PhD, led a study that surveyed ecosystems of bacteria and their capacity to resist antibiotics in low resource communities and identified areas ripe for bacteria to shuffle and share their resistance genes....More

Gordon Recognized for Leading Research on Microbiome

04/08/2016

Public research, development and manufacturing company Agilent Technologies has recognized CDI Board Member and prominent researcher Jeffrey I. Gordon, MD, with a Thought Leader Award. The award supports his research into the role of the gut microbiome in human health. Dr. Gordon's work has begun to uncover the complex relationship between the tens of trillions of microbes that live in the gastrointestinal tract, our health status and our disease risks. ...More

Preemies’ Gut Bacteria Reveal Vast Scope of Antibiotic Resistance

03/07/2016

A new study by CDI collaborators Gautam Dantas, PhD, and Barbara Warner, MD, reveals extensive antibiotic resistance in the gut bacteria of premature infants. The researchers say these findings support the push to minimize routine use of antibiotics in these patients....More

Natural Sugar May Treat Fatty Liver Disease

02/25/2016

Studying mice, pediatric gastroenterologist Brian DeBosch, MD, PhD, and his CDI-funded research team, has shown that a natural sugar called trehalose prevents the sugar fructose — thought to be a major contributor to nonalcoholic fatty liver disease — from entering the liver and triggers a cellular housekeeping process that cleans up excess fat buildup inside liver cells. The research appeared Feb. 23 in the journal Science Signaling. ...More

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