Funded Research


Status Principal Investigator(s) Center(s) Funding Mechanism Title Year of Award
Active
121
Jeffrey Bednarski, Todd Fehniger, Rizwan Romee
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Memory-like Natural Killer Cell Immunotherapy for Pediatric and Young Adult Leukemia Patients 2017 $450,000
Active
395
Hong Chen, Yongjian Liu
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Image-guided Drug Delivery for Improved Treatment of Diffuse Intrinsic Pontine Glioma 2017 $450,000
Active
410
John F. DiPersio
McDonnell Pediatric Cancer Center Large-Scale Interdisciplinary Research Initiative Clinical Development Of CRISPR/Cas9 Gene Edited CAR-T for the Treatment of T Cell Malignancies 2017 $360,000
Active
29
Todd Druley
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Functional Characterization of Rare Congenital Variation in Infantile Leukemia 2014 $450,000
Active
29
Todd Druley
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Improving Minimal Residual Disease Surveillance Of Pediatric AML Via Error-corrected Sequencing 2015 $450,000
Active
385
Karen Gauvain, David Limbrick
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative MRI-guided Laser Heat Ablation to Induce Blood Brain Barrier Breakdown in Pediatric Brain Tumors 2016 $176,661
Active
385
Karen Gauvain, Gavin Dunn
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative A Pilot Study of a Personalized Vaccine Approach in Patients with Recurrent Pediatric Brain Tumors 2017 $450
Active
342
Jeffrey Magee
McDonnell Pediatric Cancer Center Faculty Recruitment/Scholar Award The Developmental Changes in Stem Cell Self-renewal Mechanisms and Their Role in Leukemogenesis 2014 $300,000
Active
63
Robi D. Mitra
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Sex-specific Super Enhancer Activity in Glioblastoma 2016 $450,000
Active
391
Suman Mondal
McDonnell Pediatric Cancer Center Postdoctoral Fellowship Intraoperative Real-time Fluorescence Image-guided Resection of Pediatric Brain Tumors 2016 $60,000
Active
146
Joshua B. Rubin, Bradley Schlaggar
McDonnell Pediatric Cancer Center Large-Scale Interdisciplinary Research Initiative Survivors of Pediatric Brain Tumors: Biomarkers of Cognitive Dysfunction 2016 $594,000
Active
146
Joshua B. Rubin, Albert Kim, Kristen Kroll, Hiroko Yano
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Targeting The Abnormal Chromatin State Of Pediatric Brain Tumors 2015 $450,000
Active
333
Laura Schuettpelz
McDonnell Pediatric Cancer Center Faculty Recruitment/Scholar Award Elucidating the Role of KLF7 in T Cell Development 2013 $300,000
Active
388
Shalini Shenoy
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative A Phase-one Trial of Familial Haploidentical Nonmyeloablative Bone Marrow Transplantation in Children 2016 $290,000
Active
389
Qin Yang, Dennis Hallahan
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Developing a Novel Reprogramming Strategy for Pediatric Brain Tumor Treatment 2016 $125,000
Completed
121
Jeffrey Bednarski
McDonnell Pediatric Cancer Center Postdoctoral Fellowship Regulation of Transcriptional Responses to DNA Damage 2009 $60,000
Completed
123
Martha Bhattacharya
McDonnell Pediatric Cancer Center Postdoctoral Fellowship Molecular Strategies to Block Peripheral Neuropathy in Mouse Models of Vincristine Neurotoxicity 2012 $60,000
Completed
305
Grant Challen
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Altered Epigenetics as a Driver of T-cell Acute Lymphoblastic Leukemia 2013 $300,000
Completed
124
Barak Cohen
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Genetic Analysis of Human Variation in B-cell Activation 2008 $200,000
Completed
207
Megan Cooper
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Investigation of Somatic Defects in Patients with Autoimmune Diseases 2012 $450,000
Completed
125
Joseph Corbo
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Deciphering the Transcriptional Regulatory Network of Retinoblastoma 2010 $450,000
Completed
335
Vikas Dharnidharka
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Nextgen Deep Sequencing In Post-transplant Lymphoproliferative Disorders 2014 $227,741
Completed
29
Todd Druley
McDonnell Pediatric Cancer Center Faculty Recruitment/Scholar Award High-throughput Rare Variant Detection in High-risk Pediatric Acute Lymphoblastic Leukemia 2010 $300,000
Completed
29
Todd Druley
McDonnell Pediatric Cancer Center Postdoctoral Fellowship Genomic Analysis of p53 Hypermutability in High-Grade Pediatric Astrocytoma 2007 $40,000
Completed
137
Erik Herzog
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Cancer Chronotherapy: Circadian Rhythms and Tumor Biology 2008 $200,000
Completed
138
Jeffrey R. Leonard
McDonnell Pediatric Cancer Center Core Large Initiative The Brain Tumor Data Bank 2007 $350,000
Completed
138
Jeffrey R. Leonard, Joshua B. Rubin
McDonnell Pediatric Cancer Center Core Large Initiative The Brain Tumor Data Bank 2009 $700,000
Completed
63
Robi D. Mitra
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Using Polony Sequencing to Detect p53 Hypermutability in Pediatric Gliomas 2007 $200,000
Completed
369
Nima Mosammaparast
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Understanding Mechanisms of Alkylation Chemoresistance in Pediatric Glioblastoma 2015 $150,000
Completed
266
Rajalaxmi Natarajan
McDonnell Pediatric Cancer Center Postdoctoral Fellowship Identifying Interactors of Sanpodo Essential for Notch-Mediated Asymmertric Divisions in Drosophila Nervous System 2007 $40,000
Completed
146
Joshua B. Rubin
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Characterization of the Brain Tumor Microenvironment Proteome 2009 $300,000
Completed
146
Joshua B. Rubin
McDonnell Pediatric Cancer Center Large-Scale Interdisciplinary Research Initiative Identifying a Clinically Available PDE4 Inhibitor for Treatment of Children with Malignant Brain Tumors 2008 $50,000
Completed
146
Joshua B. Rubin, David Gutmann
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Sexually Dimorphic cAMP Signaling Impacts the Rate of Brain Tumors in Prepubertal Boys and Girls 2012 $300,000
Completed
153
Sheila A. Stewart
McDonnell Pediatric Cancer Center Core Large Initiative Enabling Applied Genomic Technologies in Pediatrics 2007 $600,000
Completed
158
Jason D. Weber
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Targeting Nucleolar Protein Interactions in Pediatric Gliomas 2013 $250,000
Completed
268
Karen L. Wooley
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Hyperbranched Fluoropolymers (HBFP(III)), Designed as Complex Nanostructures for Imagining and Therapeutic Delivery in Diagnosis and Treatment of Pediatric Brain Cancers 2007 $200,000
Completed
160
Zhongsheng You, David R. Piwnica-Worms
McDonnell Pediatric Cancer Center Interdisciplinary Research Initiative Targeting an Rna Surveillance Pathway in Pediatric Cancer 2012 $150,000