Human genetic and genomic studies produce an avalanche of candidate human disease genes and specific mutations that require validation in vivo. To facilitate testing candidate pediatric disease genes, generation of new zebrafish pediatric disease models and piloting chemical screens, the Children’s Discovery Institute has funded a three-year proposal to establish a Zebrafish Models for Pediatric Research Cooperative of several WUSM core facilities, including: Fish Facility (FF), Genome Technology Access Center (GTAC), Genome Engineering and iPSC Core (GEiC), WU High Throughput Screening Core (HTS), Molecular Vectors Core (MVC), WU Center for Cellular Imaging (WUCCI) and Protein & Nucleic Acid Chemistry Laboratory (PNACL).
The CDI award will support the following types of projects:
The current proposal submission period has ended. A new RFP will begin on January 1, 2018.
To obtain approximate project costs and/or request additional information regarding your research project, contact the applicable core:
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The Children's Discovery Institute, a partnership between St. Louis Children's Hospital
and Washington University School of Medicine, will accelerate cures for the most
life-threatening diseases of childhood through collaborative and interdisciplinary