2007 Articles and Releases

CDI in Bangalore, India

Tigers are fierce and aggressive and no less so is the Children’s Discovery Institute in the pursuit of newCIMG2585.JPGknowledge for child health. Lead Investigator Thomas Morgan M.D., Assistant Professor of Pediatrics, is in Bangalore, India working with Sunita Maheshwari, M.D. Chief of Cardiology at Narayana Hrudayalaya.

Tom, Sunita and colleagues are identifying the genetic factors influencing the development of congenital heart disease. Bangalore provides a compelling opportunity to undertake gene identification by a method termed homozygosity mapping in affected infants from highly inbred families. This unique resource permits the Children’s Discovery Institute the opportunity to enhance clinical care and genetic education in this region of the world and to partner with the extraordinary expertise of Sunita and her colleagues in diagnosing and treating congenital heart disease in these populations.

Tom and Sunita will then collaborate with Mike Province, Ph.D., Director of the Division of Statistical Genomics and Elaine Mardis, Ph.D., Associate Director of the Genome Sequencing Center utilizing the technological resources of Washington University School of Medicine to facilitate gene identification and with pediatric cardiologist Patrick Jay, M.D. to develop animal models of congenital heart disease based upon these discoveries. Tom recently took time out to visit the Periyar Tiger Reserve and send back evidence of his hard work.

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