A Bold New Way of Understanding the Anatomy of the Heart


The story of this Children’s Discovery Institute-funded grant started with a phone call. Washington University School of Medicine biomedical engineer Jon Silva, PhD, was at a Microsoft conference and had just seen a demonstration of the Microsoft Hololens, the first self-contained hologram computer. This technology enables its user, who is looking through specially designed goggles, to interact and engage with three-dimensional holograms in their three-dimensional space. They call it augmented reality....More

Worms at Work to Find the Origins of Disease


When it comes to childhood diseases, lysosome storage diseases probably aren’t top of mind to most people, but, Abhinav Diwan, MD, medicine, would argue that they should be. ...More

Healing a Broken Heart


Can we put immune cells to work to reverse pediatric cardiomyopathy? One CDI researcher intends to find out....More

CDI Research Suggests a Link Between Exercise and Risk for Heart Defects


Pediatric cardiologist Patrick Jay, MD, PhD, and his team applied CDI funding to a study showing that with exercise, older mouse mothers can reduce the risk of congenital heart defects in their baby mice. ...More

Study of Rare Disorder Sheds Light on Common Conditions


A CDI faculty scholar identifies genetic factors that increase the risk for vascular problems in patients with Williams syndrome, paving the way for better diagnostics and treatments for a range of diseases....More

Envisioning a Future Without Congenital Heart Disease


Through an interdisciplinary research initiative, researchers at the Children’s Discovery Institute seek to identify genetic and metabolic factors that affect the risk of developing congenital heart defects. ...More

Protecting the Brain While Repairing the Heart


Cynthia Ortinau, MD, leads a research team studying the effects of pediatric heart defects on brain development....More

Patrick Jay, MD, PhD Awarded American Heart Association Grant


Children's Discovery Institute investigator, Patrick Jay, MD, PhD, recently received the American Heart Association's National Established Investigator award. ...More

Canter Named Tuttle and Hauck Professor


Charles E. Canter, MD, has been named the first Lois B. Tuttle and Jeanne B. Hauck Chair in Pediatrics at St. Louis Children’s Hospital and Washington University School of Medicine in St. Louis....More

Human and Soil Bacteria Swap Antibiotic-Resistance Genes


Soil bacteria and bacteria that cause human diseases have recently swapped at least seven antibiotic-resistance genes, researchers at Washington University School of Medicine in St. Louis report Aug. 31 in Science. The work is funded in part by the Children’s Discovery Institute....More

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