Children's Eye Cancer
Children’s Eye Cancer: New Grant Focuses on Retinoblastoma
Retinoblastoma is a rare form of cancer that begins in the retina of the eye. It
is the most common cancer of the eye in children. According to the National Cancer
Institute, physicians diagnose about 300 children each year with retinoblastoma.
Current treatment includes chemotherapy, radiation therapy, laser, cold, or heat
treatments, and surgery. Unfortunately, children with retinoblastoma must frequently
have the affected eye surgically removed. For this reason, medical science continues
to search for “eye-sparing therapy”—that is, treatment that eradicates
the cancer while allowing a child to keep the eye and sustain normal or close-to-normal
Newly funded research: "Deciphering the transcriptional regulatory network
Under the aegis of a new grant from the Children’s Discovery Institute, Joseph
C. Corbo, MD, PhD, Division of Pathology and Immunology, Washington
University School of Medicine, will study the genetics of retinoblastoma.
Dr. Corbo and his team will test the hypothesis that retinoblastomas have genetic
and molecular features of a “cone photoreceptor precursor cell”—the
immature stage of cone cells in the retina that, along with rod cells, make vision
possible. Based on their hypothesis, the team will also test a new, potentially
eye-sparing treatment for retinoblastoma.
To learn more about Dr. Corbo's work and lab, click
here to visit his Funded Research page