In children, respiratory, sinus, and ear disease can result from dysfunction of the cilia—tiny, hairlike structures in the lungs, nose, sinuses, and ears. Now, with help from the Children’s Discovery Institute, a unique team composed of a physician, a geneticist, and a mechanical engineer is tackling the problem. ... more

April 20, 2009 -- The search for the cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds light on the development of other cancers. ... more

A problem as simple as a ruptured appendix can quickly become a life-threatening event for a child. Even with prompt surgery and excellent post-operative care, children occasionally develop sepsis syndrome, a complex systemic inflammatory condition which can complicate an otherwise treatable infection. In the United States, children who develop sepsis syndrome have a 1 in 10 chance of dying, accounting for about 4,300 preventable deaths annually. ... more