"Because there was so much research going on in St. Louis, we knew we could come here for answers."--Gina White, mother of Elliana ... more

In children, respiratory, sinus, and ear disease can result from dysfunction of the cilia—tiny, hairlike structures in the lungs, nose, sinuses, and ears. Now, with help from the Children’s Discovery Institute, a unique team composed of a physician, a geneticist, and a mechanical engineer is tackling the problem. ... more

April 20, 2009 -- The search for the cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds light on the development of other cancers. ... more

A problem as simple as a ruptured appendix can quickly become a life-threatening event for a child. Even with prompt surgery and excellent post-operative care, children occasionally develop sepsis syndrome, a complex systemic inflammatory condition which can complicate an otherwise treatable infection. In the United States, children who develop sepsis syndrome have a 1 in 10 chance of dying, accounting for about 4,300 preventable deaths annually. ... more