Learn how this image helps us understand kids with heart failure ... more

Investors and investigators gather to share, discuss progress ... more

Bringing new technologies to pediatric medical research is the focus of four new awards granted to researchers at Washington University by the Children’s Discovery Institute ... more

Although childhood cancer is rare, it is still the leading cause of death by disease in children age 14 and younger. Sadly, the genetic causes of some of the most devastating childhood cancers remain a mystery. ... more

Genetic factors and errors in cell development play a prominent role in childhood cancers. During development of the immune system, lymphocyte cells must create intentional breaks in DNA in order to create a diverse immune system. ... more

Robert Baloh, MD, PhD, returned to his medical roots in 2005, when he accepted a Fellowship in neuromuscular diseases at Washington University School of Medicine. Four years earlier, he had completed Washington University’s Medical Scientist Training Program before heading to Harvard for a medical internship and a residency in neurology. ... more

Malaria is the fourth most common cause of all deaths of children under the age of five. Because of the rapid spread of drug resistance to current treatments, new anti-malarial agents are badly needed. Two Discovery Institute investigators have combined their expertise to help find them. ... more

Testing a Novel Therapy ....Patrick Jay, MD, PhD ... more

Most of us take for granted that our bowels work normally. But their function depends on the proper development of an estimated 500 million nerve cells in the bowel called the enteric nervous system. ... more

Some neural tube defects in mice linked to enzyme deficiency There are birth defects that don't respond to folic acid but may respond to inositol treatment. ... more