More than 3,000 new cases of childhood brain tumors are diagnosed each year, mostly in infants and young children. Brain tumors are the second most common childhood malignancy and the most common solid tumor among children. Unlike many other cancers where the cure rates have improved significantly in recent years, most brain tumors still have an almost uniformly fatal outcome. Those who do survive the aggressive surgeries, radiation and chemotherapy treatments often are left with severe handicaps, learning disabilities or hearing and vision losses.
The McDonnell Pediatric Cancer Center conducts both clinical and research programs designed to identify key genetic features and the biological nature of different tumor groups, which will lead to improved diagnostics and therapies. The goals include development of treatment strategies that will extend lives or cure children with brain tumors while minimizing the deleterious effects of cancer therapies optimizing the quality of life.
Currently Funded Research
Featured Research:
Circadian Rhythms and Tumor Biology – Erik Herzog, Ph.D.
Nanostructures in the Diagnosis and Treatment of Pediatric Brain Cancer - Karen Wooley, Ph.D.
Members
| Jonathan D. Gitlin, M.D. |
Roberson Prof. of Pediatrics, Interim Director |
| Barak Cohen, Ph.D. |
Assistant Professor of Genetics |
| Robert J. Hayashi, M.D. |
Associate Professor of Pediatrics |
| Jeffrey R. Leonard, M.D. |
Assistant Professor of Neurologic Surgery |
| David B. Mansur, M.D. |
Assistant Professor of Radiation Oncology |
| Elaine R. Mardis, Ph.D. |
Associate Professor of Genetics |
| Jeffrey S. McKinney, M.D. |
Assistant Professor of Pediatrics |
| Arie Perry, M.D. |
Associate Professor of Pathology |
| Helen M. Piwnica-Worms, Ph.D. |
Professor of Cell Biology & Physiology |
| David R. Piwnica-Worms, M.D., Ph.D. |
Professor of Radiology |
| Joshua B. Rubin, M.D., Ph.D. |
Assistant Professor of Pediatrics |
| Sheila A. Stewart, Ph.D. |
Assistant Professor of Cell Biology |
| R. Reid Townsend, M.D., Ph.D. |
Associate Professor of Medicine |
| Jason D. Weber, Ph.D. |
Assistant Professor of Medicine |
| Karen L. Wooley, Ph.D. |
McDonnell Professor of Chemistry |