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  McDonnell Pediatric Cancer Center

Overview


More than 3,000 new cases of childhood brain tumors are diagnosed each year, mostly in infants and young children. Brain tumors are the second most common childhood malignancy and the most common solid tumor among children. Unlike many other cancers where the cure rates have improved significantly in recent years, most brain tumors still have an almost uniformly fatal outcome. Those who do survive the aggressive surgeries, radiation and chemotherapy treatments often are left with severe handicaps, learning disabilities or hearing and vision losses.

The McDonnell Pediatric Cancer Center conducts both clinical and research programs designed to identify key genetic features and the biological nature of different tumor groups, which will lead to improved diagnostics and therapies. The goals include development of treatment strategies that will extend lives or cure children with brain tumors while minimizing the deleterious effects of cancer therapies optimizing the quality of life.

Currently Funded Research

Featured Research:

Circadian Rhythms and Tumor Biology – Erik Herzog, Ph.D.

Nanostructures in the Diagnosis and Treatment of Pediatric Brain Cancer - Karen Wooley, Ph.D.

Members

Jonathan D. Gitlin, M.D. Roberson Prof. of Pediatrics, Interim Director
Barak Cohen, Ph.D. Assistant Professor of Genetics
Robert J. Hayashi, M.D. Associate Professor of Pediatrics
Jeffrey R. Leonard, M.D. Assistant Professor of Neurologic Surgery
David B. Mansur, M.D. Assistant Professor of Radiation Oncology
Elaine R. Mardis, Ph.D. Associate Professor of Genetics
Jeffrey S. McKinney, M.D. Assistant Professor of Pediatrics
Arie Perry, M.D. Associate Professor of Pathology
Helen M. Piwnica-Worms, Ph.D. Professor of Cell Biology & Physiology
David R. Piwnica-Worms, M.D., Ph.D. Professor of Radiology
Joshua B. Rubin, M.D., Ph.D. Assistant Professor of Pediatrics
Sheila A. Stewart, Ph.D. Assistant Professor of Cell Biology
R. Reid Townsend, M.D., Ph.D. Associate Professor of Medicine
Jason D. Weber, Ph.D. Assistant Professor of Medicine
Karen L. Wooley, Ph.D. McDonnell Professor of Chemistry

Last Updated: Apr 2008