Funded Research

The Genetic Basis of Musculoskeletal Birth Defects
Principal Investigator(s):
  • Center for Metabolism and Immunity
Award Mechanism:
Educational Initiative
Project Period:
2/1/2007 - 7/1/2009
Total Amount:
This award provides funding for a unique two-day educational symposium that is integral to understanding the genetic basis of musculoskeletal birth defects. This annual symposium is vital to the support and development of this line of research. Despite the use of the limb over several decades as a classical developmental model, the genetic analysis of human limb malformation has been a relatively neglected subject. The symposium focuses on the genetics of human limb malformations and provides a unique opportunity for a multi-disciplinary conference that includes the Departments of Pediatrics, Orthopaedic Surgery, Neurology, Genetics, Development Biology, and Statistics.
Project Update:
The Institute funded symposium has been completed. Scientists shared their experience and observations on a wide range of musculoskeletal birth defects—from cutting edge research to general reviews that appealed to a broad audience and it was a huge success. Invited speakers from outside Washington University included William Cole, MD from University of Alberta and Carol Wise, MD from Texas Scottish Rite Hospital in Dallas. Christina Gurnett, MD, PhD and Fanxin Long, PhD were the invited lecturers from within Washington University. 

Attendance at the symposium was excellent, out there were wonderful interactions throughout the day. Since the response was overwhelmingly positive from all involved, we plan to hold this event on an annual basis.