Funded Research

Electrocardiographic Imaging in Congenital Heart Disease Following Repair
Principal Investigator(s):
  • Congenital Heart Disease Center
Award Mechanism:
Core Large Initiative
Project Period:
7/1/2009 - 6/30/2012
Total Amount:
Yoram Rudy
Electrocardiographic imaging (ECGI) is a novel imaging modality that accurately represents electrical potentials and activation patterns from the surface of the heart in a non-invasive manner. ECGI has shown potential in assessing cardiac electrophysiological abnormalities in both adults and pediatric patients. This core provides a recording system for use primarily at St. Louis Children’s Hospital. This is a highly multidisciplinary project that involves investigators from pediatric cardiology, biomedical engineering, and pediatric cardiac surgery. Specific investigations that will benefit from the availability of this instrument involve patients with congenital heart disease (CHD), specifically two groups: patients who have undergone surgical repair for Tetralogy of Fallot (TOF) who are at risk for ventricular tachycardia and sudden death, and patients with complex CHD and ventricular dyssynchrony. Knowledge gained from these studies will allow us to offer better treatments for such patients. George F. Van Hare, MD, Director of the Division of Pediatric Cardiology. Dr. Van Hare is the Louis Larrick Ward Professor of Pediatrics at Washington University School of Medicine. He trained in pediatrics at Rainbow Babies and Children's Hospital in Cleveland, Ohio, and in pediatric cardiology at the Cardiovascular Research Institute of the University of California, San Francisco. He has a special interest and expertise in pediatric cardiac electrophysiology, including catheter ablation and the implantation and management of pacemakers and implantable cardioverter-defibrillators. He is a fellow of the American College of Cardiology, the American Academy of Pediatrics and the Heart Rhythm Society.